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. 2013 Jul 18;32(4):775–784. doi: 10.3892/ijmm.2013.1449

Figure 1.

Figure 1

Effects of piceatannol and resveratrol on matrix metalloproteinase-2 (MMP-2) activity in H-ras MCF10A cells. (A) Chemical structures of piceatannol and resveratrol. (B) Effect of piceatannol and resveratrol on MMP-2 activity in H-ras MCF10A cells. Cells were starved in serum-free DMEM/F12 for 24 h and then treated with samples at the indicated concentrations for 24 h. The conditioned medium was analyzed by zymography, as described in Materials and methods. (C) The relative level of MMP-2 activity was quantified densitometrically using Image J software. Data are representative of three independent experiments that produced similar results. (D) Effects of piceatannol and resveratrol on H-ras MCF10A cell viability. Cells were treated for 24 h in the presence or absence of piceatannol or resveratrol. Cell viability was quantified using MTT assay, as described in Materials and methods. Data are the means ± SD of three independent experiments.