. Author manuscript; available in PMC: 2014 Nov 1.

Published in final edited form as: J Pediatr. 2013 Jul 26;163(5):10.1016/j.jpeds.2013.06.025. doi: 10.1016/j.jpeds.2013.06.025

Table 2.

Genotype frequencies and p values in cases with Grade 3 – 4 IVH and controls

Gene	Variant	Genotype	Number (%)		P value
Gene	Variant	Genotype	Controls	Cases	P value

COL4A1	p.Gly1580Arg⁸ rs3825481^*	AA	85.8	87.4	0.817
		AG	13.9	12.6
		GG	0.3	0.0

F2	c.97G>A^7,13 rs5898^*	GG	84.5	79.9	0.306
		GA	14.5	19.2
		AA	1.0	0.9

F5	c.1601G>A^6,7,13 rs6015^*	CC	84.3	83.5	0.919
		CT	15.2	16.1
		TT	0.5	0.5

IL1B	c.-87-511T>C^6,14 rs16944	GG	41.4	37.5	0.206
		AG	44.7	51.8
		AA	13.9	10.7

	c.-87-31C>T¹⁴ rs1143627	TT	41.4	37.1	0.184
		CT	44.7	52.2
		CC	13.9	10.7

IL6	c.-116-121C>G¹⁵ rs1800797^*	GG	35.7	33.9	0.873
		AG	46.8	47.3
		AA	17.5	18.8

MTHFR	c.677C>T⁷ rs1801133	CC	42.4	43.8	0.782
		CT	44.5	45.1
		TT	13.1	11.2

	c.1298A>C⁷ rs1801131	AA	54.8	43.8	0.021
		AC	37.0	48.2
		CC	8.2	8.0

TNF	c.-169-319G>A¹⁶ rs1800629	GG	68.4	70.5	0.843
		AG	29.3	27.7
		AA	2.3	1.8

Proxy SNP