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. 2013 Feb 12;14(1):35–40. doi: 10.1038/tpj.2013.3

Figure 1.

Figure 1

Genome-wide association study (GWAS) meta-analysis Manhattan plot showing the association of triglyceride response to hydrochlorothiazide (HCTZ) treatment in African Americans in the Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR) and the Genetic Epidemiology of Responses to Antihypertensive (GERA) studies. Two single nucleotide polymorphisms (SNPs) on chromosome 11 showed genome-wide significance (P=5 × 10−8). Eighteen loci showed P-values less than the suggestive threshold (P=1 × 10−5).