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. Author manuscript; available in PMC: 2014 Mar 1.
Published in final edited form as: Amino Acids. 2013 Jul 3;46(3):531–542. doi: 10.1007/s00726-013-1531-z

Figure 4.

Figure 4

Effects of SMO overexpression on levels of spermine and L-Arg uptake. RAW 267.4 cells were transiently transfected with vector alone or vector containing SMO cDNA. Transfected cells were activated with HPL at an MOI of 100. (A) SMO activity. (B) Levels of spermine at the times indicated. (C) L-Arg uptake, assessed as transport of 14C-L-Arg into cells at the times indicated. In A–C, data are from 3 experiments performed in duplicate. *p < 0.05; **p < 0.01, ***p < 0.001 vs unstimulated control cells transfected with empty vector; and §p < 0.05; §§p < 0.01 vs HPL-stimulated cells transfected with the empty vector.