Table 4.
Crude and adjusted correlations between total cortisol AUC and other cortisol features measured on the same day.
| Feature | Unadjusted a |
Partially adjusted b |
Fully adjusted c |
|||
|---|---|---|---|---|---|---|
| Correlation (95% CI) | P-Value | Correlation (95% CI) | P-Value | Correlation (95% CI) | P-Value | |
| Wake up (A) | 0.39 (0.34 to 0.43) | <0.0001 | 0.36 (0.32 to 0.41) | <0.0001 | 0.36 (0.32 to 0.4) | <0.0001 |
| Bedtime (H) | 0.64 (0.61 to 0.66) | <0.0001 | 0.61 (0.58 to 0.64) | <0.0001 | 0.61 (0.58 to 0.64) | <0.0001 |
| Early decline slope (C) | 0.11 (−0.01 to 0.23) | 0.076 | 0.11 (−0.02 to 0.24) | 0.080 | 0.12 (−0.02 to 0.25) | 0.086 |
| Late decline slope (D) | 0.21 (0.16 to 0.26) | <0.0001 | 0.19 (0.14 to 0.24) | <0.0001 | 0.18 (0.13 to 0.23) | <0.0001 |
| Total AUC (E + F + G) | 0.02 (−0.03 to 0.07) | 0.50 | 0.03 (−0.02 to 0.08) | 0.28 | 0.04 (−0.01 to 0.09) | 0.13 |
| CAR AUC (E) | 0.44 (0.40 to 0.48) | <0.0001 | 0.42 (0.38 to 0.46) | <0.0001 | 0.42 (0.38 to 0.46) | <0.0001 |
| Early decline AUC (F) | 0.55 (0.52 to 0.59) | <0.0001 | 0.54 (0.5 to 0.57) | <0.0001 | 0.54 (0.50 to 0.58) | <0.0001 |
| Late decline AUC (G) | 0.99 (0.99 to 0.99) | <0.0001 | 0.99 (0.99 to 0.99) | <0.0001 | 0.99 (0.99 to 0.99) | <0.0001 |
Only adjusted for wake up time.
Adjusted for wake up time, age, sex, race/ethnicity.
Partially adjusted + diabetes status, smoking, use of beta blockers, body mass index, income, education, Center for Epidemiological Studies Depression scale (CES-D) score.