. Author manuscript; available in PMC: 2014 Nov 1.

Published in final edited form as: J Pediatr. 2013 Aug 20;163(5):10.1016/j.jpeds.2013.07.002. doi: 10.1016/j.jpeds.2013.07.002

Table 2.

LSmeans(SE) Vascular Response Measures

	Tanner I (n=124)	Tanner II–IV (n=105)	Tanner V (n=115)	Overall P-value	Tanner I vs. II–IV	Tanner I vs. V	Tanner II–IV vs. V
Baseline Diameter, mm	2.96(0.07)	3.17(0.04)	3.34(0.07)	0.012	0.014	0.003	0.028
FMD (%)	8.6(0.59)	7.96(0.37)	7.88(0.58)	0.68	0.39	0.52	0.90
FMD-AUC, %-s⁻¹	805.4(74.5)	772.9(46.5)	786.1(73.5)	0.91	0.72	0.89	0.87
EID (%)	23.7(1.40)	24.4(0.67)	24.5(0.77)	0.88	0.61	0.67	0.91
EID-AUC, %-s⁻¹	3870.3(264.8)	3768.7(126.1)	3758.0(141.1)	0.92	0.69	0.76	0.96
DD, %	14.5(0.59)	15.1(0.37)	15.4(0.58)	0.66	0.37	0.41	0.71
CSD, %	31.2(1.4)	32.7(0.85)	33.2(1.3)	0.66	0.37	0.42	0.71
DC, mm-mmHg⁻¹	0.013(0.002)	0.018(0.001)	0.018(0.002)	0.18	0.06	0.17	0.81
CSC, mm²-mmHg⁻¹	0.18(0.008)	0.16(0.005)	0.16(0.008)	0.41	0.19	0.22	0.54

LSmeans(SE) adjusted for Age, Sex, Race, and Baseline Diameter. P-values <0.05 demonstrate significant differences among Tanner stages I, II–IV, and V. Baseline diameter (baseline brachial artery diameter at rest); FMD, flow-mediated dilation; FMD-AUC, flow-mediated dilation area-under-the-curve; EID, endothelium-independent dilation; EID-AUC, endothelium-independent dilation area-under-the-curve; DD, diameter distensibility; CSD, cross-sectional distensibility; DC, diameter compliance; CSC, cross-sectional compliance.