Table 2.
Univariate and multivariate regression analyses of the association of clinical features with radiotherapy response of rectal adenocarcinoma n (%)
| Clinicopathological factors |
Univariate analysis |
Multivariate analysis |
||
| Good response1 | P value | OR | P value | |
| Gender | ||||
| Male | 15 (13.8) | 0.697 | NS | |
| Female | 3 (10.7) | |||
| Age (yr) | ||||
| ≤ 55 | 5 (26.3) | 0.129 | NS | |
| > 55 | 13 (11.1) | |||
| Tumor size (cm) | ||||
| ≤ 5 | 16 (20.5) | < 0.001 | 5.058 | < 0.001 |
| > 5 | 2 (3.5) | |||
| Tumor cell differentiation | ||||
| Well/moderately differentiated | 4 (4.1) | < 0.001 | 4.692 | < 0.001 |
| Poorly differentiated | 14 (36.8) | |||
| Tumor invasion depth | ||||
| T1/T2 | 7 (30.4) | 0.027 | 1.143 | 0.053 |
| T3/T4 | 11 (9.7) | |||
| Nuclear β-catenin expression | ||||
| ≤ 50% | 15 (23.1) | < 0.001 | 6.375 | < 0.001 |
| > 50% | 3 (4.2) | |||
1
Tumor regression grading ≥ 3. NS: Not selected.