Figure 3.

COC-treated animals show deficits specific to reversal learning. A, No effects of treatment on initial response discrimination or (B) response retention. C, COC animals are significantly impaired on reversal learning measured as both total errors made or total trials to criterion. Analysis of error types revealed no difference in perseverative errors but increased regressive errors in COC animals. *, significantly different from saline-treated. D, No group difference in any measure of set-shifting performance.