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. Author manuscript; available in PMC: 2013 Oct 30.
Published in final edited form as: Pain. 2011 Jan 20;152(3):10.1016/j.pain.2010.11.021. doi: 10.1016/j.pain.2010.11.021

Fig. 1.

Fig. 1

Lateral paw incision increases the response rates to simulation by von Frey hairs of the lateral paw area that are reduced by preincisional injection of RvD1. Thirty minutes before the incision, 20 ng of RvD1 was injected intrathecally; testing occurred at 1 and 6 hours postincisional, and then at each day including POD 10. Appearance of responses to weak von Frey hairs (A, B: 4 and 6 g) indicates allodynia, and the increase in response to strong von Frey hairs (C, D: 10 and 15 g) indicates hyperalgesia. Comparison of vehicle-injected and RvD1-injected rats, at respective times after incision: *P < .05; **P < .01; ***P < .001 (1-way ANOVA).