Table II.

Performance of depth and sterile filtration for SmP treated cultures

Flocculation conditions	mAb	Depth filter	Max ΔP (psi)	Capacity (L/m2)	Pool turbidity (NTU)	Sterile filter	Sterile filter capacity (L/m2)
Untreated	Mab-A	D0HC/X0HC	22.0	70	1.35	SHC	>10,000
0.1% SmP E, pH 7.0, 50 mM NaPi	Mab-A	40MS	11.8	261	1.19	SHF	>10,000
0.1% SmP E, pH 7.0, 50 mM NaPi	Mab-A	60HX	4.9	254	1.91	SHF	8,900
0.2% SmP E, pH 7.0, 50 mM NaPi	Mab-A	40MS	9.8	319	1.54	SHF	>10,000
0.2% SmP E, pH 7.0, 50 mM NaPi	Mab-A	60HX	10.1	329	1.22	SHF	>10,000
0.2% SmP E, pH 6.5, 25 mM NaPi	Mab-T	40MS	20.0	385	2.11	SHF	>10,000
0.2% SmP E, pH 6.51, 25 mM NaPi	Mab-T	40MS	12.0	588	2.25	SHF	>10,000
0.4% SmP E, pH 7.01, 10 mM NaPi	Mab-T	40MS	20.0	294	2.35	SHF	>10,000
0.2% SmP E, pH 6.5, 25 mM NaPi	Mab-T	60HX	20.0	327	2.96	SHF	>10,000
0.2% SmP E, pH 6.51, 25 mM NaPi	Mab-T	60HX	20.0	310	3.32	SHF	>10,000
0.4% SmP E, pH 7.01, 10 mM NaPi	Mab-T	60HX	20.0	310	3.25	SHF	>10,000

Untagged SmP E.