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(A) Disconnection of dictyostatin into 3 fragments of similar complexity; (B) The “Roche ester strategy” for the synthesis of functionalized stereotriads; (C) A hypothetical one-step stereotriad synthesis from aldehyde 4; (D) A proposal for the one-pot synthesis of the C(12)-C(14) and C(20)-C(22) stereotriads of dictyostatin.
