Mean density of collagen VI in inferior oblique muscles. Results are compared from controls, patients whose angle of misalignment varied in their two eyes, and those where similar angles of misalignment were seen. Data is expressed as percent expression of collagen VI per muscle area and presented as the mean ±1 standard error of the mean (SEM). Asterisk (*) indicates significantly different from control values at P<.05; # sign indicates significantly different from contralateral side at P<.05. IO, inferior oblique; IOOA, inferior oblique overaction; NPS, no prior surgery.