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. 2012 Jun 6;27(1):13–22.

Table 1.

Spectroscopy data

Authors Scanner Type H-MRS TE (ms) Voxel volume (cm3) Markers Type Region of interest
Sequence TR (ms)
Bernier D 200918 1.5T GE scanner Single voxel ___ 2000 30 1.6×1.6×1.6 (DPFA)
1.3×1.3×1.3 (PONS)
Cho, Cr, NAA Left DPFA and pons
Block W 200917 3T Gyroscan Achieva Philips Single voxel PRESS 2000 140 and 30 2.8×1.7×1.3 NAA, Cr, Cho, ml, Gln, Glx and Gln/Glx and Gln/Cr Hippocampus body,parts of its head, of the amygdala and of parahippocampal gyrus
Murck H 200916 1.5T Signa Horizon Single voxel PRESS 2000 and 4000 35 0.58×0.58×0.58 (DLPFC) and 1.75×1.75×1.75 (POC) Cho, Cr, NAA, Glx,Gln DLPFC and POC
Luborzewski A 200715 3T Medspec Bruker Biospin Single voxel PRESS 3000 80 2×2×2 (DLPFC); 2.5×4×2 (ACC) Cho, Cr, NAA, Glu, Gln DLPFC and ACC
Gonul AS 200614 1.5T Magnetom Vision, Siemens Single voxel PRESS 1500 135 2×2×2 NAA, Cr, Cho, ml and NAA/Cr, Cho/Cr Medial frontal cortex
Sanacora G 200613 2.1T Oxford Magnet, Bruker Avance Single voxel (2 subspectra of 128 scans) J-editing pulse sequence 3390 80 3.9×1.5×3.5 GABA Midline of occipital cortex
Michael N 200312 1.5T Magnetom Sp, Siemens Single voxel (128 scans) STEAM 2500 20 3.375 Cho, Cr, NAA, Glx Left amygdalar region
Michael N 200311 1.5T Magnetom Sp, Siemens Single voxel (128 scans) STEAM 2500 20 3.375 Cho, Cr, NAA, Glx DLPFC
Obergriesser T 200310 1.5T Siemens Single-voxel PRESS 1800 135 ___ Cho, Cr, NAA Left and right hippocampus
Pfleiderer B 20039 1.5T Magnetom Sp, Siemens Single voxel STEAM 2500 20 3.375 Glx, Cho, Cr, NAA Left anterior (pregenual) cingulum
Sanacora G 20038 2.1T Oxford Magnet, Bruker Avance Single voxel (2 subspectra of 128 scans) J-editing pulse sequence 3390 68 1.5×3×3 GABA Midline of occipital cortex
Sanacora G 20027 2.1T Oxford Magnet, Bruker Avance Single voxel (2 subspectra of 128 scans) J-editing pulse sequence 3390 68 1.5×3×3 GABA Midline of occipital cortex
Ende G 20006 1.5T Siemens Vision Single-voxel PRESS 1800 135 ___ Cho, Cr, NAA Left and right hippocampus
Sonawalla SB 19995 1.5T Signa General Electric Medical System Single voxel STEAM 2000 30 8 Cho/Cr and NAA/Cr Head of left caudate and putamen
Charles HC 19944 1.5T GE Signa Single voxel STEAM 2000 ___ 3 NAA/Cr, NAA/Cho, Cho/Cr Basal ganglia and thalamus

Abbreviations: NAA=N-acetylaspartate; Cr=creatine; Cho=choline-containing compounds; m=myoinositol; Glu=glutamate; Glx=glutamate and glutamine; Gln=Glutamine; GABA=γ-aminobutyric acid; ACC=anterior cingulate cortex; DLPFC=left dorsolateral prefrontal cortex; DPFA=dorsal prefrontal area; POC=parieto-occipital cortex; MDD=major depressive disorder.