Table 1.
C57BL/6J | BXD16 | ||
Automated home cage | |||
Total distance during dark phase | m | 280.51+/−8.02 | 247.46+/−20.43 |
Total distance during light phase | m | 40.66+/−2.02 | 36.21+/−9.87 |
Novelty induced hypophagia | |||
Latency to eat in home cage | sec | 31.83+/−4.86 | 66.29+/−18.13* |
Latency to eat in novel home cage | sec | 150.84+/−15.80 | 143.54+/−62.09 |
Novel object exploration | |||
Latency to explore novel object | sec | 47.97+/−6.41 | 53.26+/−22.18 |
Duration exploration novel object | sec | 20.45+/−1.88 | 25.22+/−4.00 |
Dark Light box | |||
Duration in the light | sec | 344.04+/−6.01 | 292.28+/−20.37** |
Entries into the light | number | 44.33+/−1.29 | 35.00+/−3.01** |
Elevated plus maze | |||
Duration on the open arms | sec | 22.85+/−2.33 | 4.61+/−1.91*** |
Entries into open arms | number | 5.21+/−0.4 | 1.92+/−0.60*** |
Entries into center | number | 28.29+/−0.92 | 14.33+/−1.94*** |
Entries into closed arms | number | 23.71+/−0.8 | 13.08+/−1.64*** |
Latency to enter the center | sec | 9.53+/−0.96 | 28.81+/−15.02* |
Open Field | |||
Total distance traveled | cm | 5081.78+/−141.59 | 3272.30+/−364.36*** |
Duration in center | sec | 68.87+/−3.5 | 60.52+/−14.94 |
Entries into center | number | 44.17+/−2.08 | 30.67+/−5.72* |
Number of progressions | number | 152.79+/−4.33 | 100.25+/−13.20*** |
Distance traveled per progression | cm | 25.52+/−0.68 | 24.00+/−3.18 |
Duration of a lingering episode | sec | 1.19+/−0.05 | 1.97+/−0.32*** |
Duration of a progression | sec | 1.54+/−0.03 | 1.67+/−0.16 |
Acceleration | cm/sec2 | 16.12+/−0.25 | 12.93+/−0.62*** |
Number of stops per distance | number/cm | 0.03+/−0.00 | 0.03+/−0.01 |
*P < 0.05, **P < 0.01, ***P < 0.001.