Relationships between brain volume reductions and palpebral fissure length (PFL) after controlling for scan location, age, sex, and ICV in subjects with FASD Inferior view of the brain, showing the regions in which smaller PFL was associated with smaller subcortical volumes in the FASD group (n = 52). After controlling for site, age, sex, and ICV in multiple regression analyses, areas in gray represent regions where this relationship was no loner significant. Areas displayed in color represent regions where these results remained significant (P < 0.05, in the left and right ventral diencephalon). Residual plots corresponding to these regions are displayed on the side.