TABLE 1.
CEA (ng/mL)
|
CA 19-9 (U/mL)
|
CA-125 (kU/mL)
|
|||||||
---|---|---|---|---|---|---|---|---|---|
≤5, n (%) | > 5, n (%) | p value | ≤37, n (%) | > 37, n (%) | p value | ≤35, n (%) | > 3, n (%) | p value | |
Overall | 72 (46) | 85 (54) | 58 (52) | 53 (48) | 56 (53) | 50 (47) | |||
Age, mean | 53.9 | 57 | .2 | 56.1 | 53.9 | .3 | 55.9 | 55.3 | .8 |
Gender | .2 | .3 | .4 | ||||||
Male | 39 (54) | 37 (44) | 29 (50) | 21 (40) | 20 (36) | 22 (44) | |||
Female | 33 (46) | 48 (56) | 29 (50) | 32 (60) | 36 (64) | 28 (56) | |||
ASA | .1 | .4 | .5 | ||||||
1 | 1 (2) | 0 (0) | 0 (0) | 1 (2) | 1 (2) | 0 (0) | |||
2 | 15 (25) | 8 (12) | 8 (16) | 7 (16) | 9 (19) | 6 (14) | |||
3 | 36 (61) | 42 (66) | 36 (74) | 27 (61) | 31 (66) | 27 (64) | |||
4 | 7 (12) | 14 (22) | 5 (10) | 9 (21) | 6 (13) | 9 (22) | |||
Recurrent disease | 27 (38) | 50 (60) | .01 | 22 (38) | 33 (64) | .01 | 32 (57) | 19 (39) | .08 |
Symptomatic | 51 (71) | 50 (59) | .1 | 36 (62) | 35 (66) | .7 | 31 (55) | 33 (66) | .3 |
CT evident disease | 47 (65) | 55 (66) | 1 | 37 (65) | 32 (60) | .7 | 27 (49) | 36 (72) | .02 |
Prior chemotherapy | 28 (39) | 34 (40) | 1 | 19 (33) | 23 (43) | .3 | 22 (39) | 17 (34) | .7 |
Prior HIPEC | 1 (1) | 8 (10) | .04 | 1 (2) | 4 (8) | .2 | 3 (5) | 1 (2) | .6 |
Prior CRS | 21 (45) | 29 (59) | .2 | 15 (40) | 19 (63) | .09 | 16 (43) | 13 (50) | .6 |
SPCI, median | 12 | 14 | .0002 | 13 | 16 | .0001 | 12 | 15 | .000007 |
Complete cytoreduction | 57 (80) | 67 (80) | 1.0 | 48 (83) | 40 (77) | .5 | 46 (82) | 37 (76) | .5 |
Diagnosis | .2 | .7 | .7 | ||||||
DPAM | 14 (19) | 24 (29) | 13 (22) | 14 (27) | 16 (29) | 12 (24) | |||
PMCA | 58 (81) | 60 (71) | 45 (78) | 38 (73) | 40 (71) | 37 (76) | |||
High grade | 37 (51) | 22 (26) | .002 | 24 (41) | 18 (34) | .4 | 18 (32) | 21 (42) | .3 |
Signet cells | 21 (29) | 9 (11) | .004 | 15 (26) | 9 (17) | .4 | 13 (23) | 8 (16) | .5 |
Lymph node metastases | 16 (30) | 9 (16) | .1 | 10 (22) | 9 (23) | 1 | 10 (24) | 6 (15) | .4 |