Table 5.
Inter-iFC between ICNs | Healthy controls |
BPD patients |
Two-sample t-test (p) | ||||
---|---|---|---|---|---|---|---|
SEM | Mean | One-sample t-test (p) | SEM | Mean | One-sample t-test (p) | ||
aDMN–aSN | 0.083 | -0.089 | 0.300 | 0.112 | 0.144 | 0.220 | 0.177 |
aDMN–lCEN | 0.059 | 0.472 | 0.000** | 0.059 | -0.036 | 0.550 | 0.000** |
aDMN–pDMN | 0.077 | 0.391 | 0.000** | 0.086 | 0.417 | 0.000** | 0.887 |
aDMN–pSN | 0.067 | 0.361 | 0.000** | 0.073 | -0.063 | 0.406 | 0.000** |
aDMN–rCEN | 0.075 | 0.348 | 0.000** | 0.086 | 0.262 | 0.010* | 0.574 |
aSN–lCEN | 0.089 | -0.392 | 0.001** | 0.079 | 0.014 | 0.860 | 0.003** |
aSN–pSN | 0.056 | 0.041 | 0.472 | 0.075 | 0.372 | 0.000** | 0.009** |
aSN–rCEN | 0.084 | -0.150 | 0.095 | 0.118 | -0.017 | 0.889 | 0.323 |
lCEN–pDMN | 0.064 | 0.563 | 0.000** | 0.062 | -0.112 | 0.095 | 0.000** |
lCEN–pSN | 0.090 | -0.057 | 0.534 | 0.052 | -0.035 | 0.507 | 0.783 |
lCEN–rCEN | 0.112 | 0.236 | 0.053 | 0.097 | 0.056 | 0.574 | 0.220 |
pDMN–aSN | 0.061 | -0.347 | 0.000** | 0.081 | -0.236 | 0.012* | 0.461 |
pDMN–pSN | 0.082 | -0.019 | 0.824 | 0.076 | -0.446 | 0.000** | 0.003** |
pDMN–rCEN | 0.083 | 0.354 | 0.001** | 0.093 | 0.437 | 0.000** | 0.672 |
rCEN–pSN | 0.077 | 0.354 | 0.000** | 0.089 | -0.252 | 0.014* | 0.000** |
One-sample and two-sample t-tests (*p < 0.05 uncorrected, **p < 0.05, Bonferroni-corrected for 15 tests) including CPZ-equivalent doses as covariate-of-no-interest, for inter-iFC between intrinsic networks in healthy controls and patients with BPD (mean and standard error of Fisher r-to-z-transformed Pearson’s correlation coefficient among network time courses). aDMN, pDMN, anterior and posterior default mode network; aSN, pSN, anterior and posterior salience network; lCEN, rCEN, left and right central executive network.