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. Author manuscript; available in PMC: 2014 Jun 1.
Published in final edited form as: Schizophr Res. 2013 Apr 6;147(1):10.1016/j.schres.2013.02.017. doi: 10.1016/j.schres.2013.02.017

Figure 4.

Figure 4

Mean COX-1 (A) COX-2 (C) and synaptophysin (G) protein levels (with representative immunoblots) in frontal cortex from control (n = 10) and SZ (n = 10) subjects. Bar graphs are ratios of optical densities of COX-1, COX-2 and synaptophysin to β-actin, expressed as percent of control. Mean protein levels of BDNF (E) in frontal cortex from control (n = 10) and SZ (n = 10) subjects and measured using ELISA. ** p < 0.01, *** p < 0.001. COX-1 (B), COX-2 (D), BDNF (F) and synaptophysin (H) mRNA levels in postmortem frontal cortex from control (n = 10) and SZ (n = 10) subjects, measured using quantitative RT-PCR. Data are levels of COX-1, COX-2, BDNF and synaptophysin in SZ normalized to the endogenous control (β-globulin) and relative to the control (calibrator), using the ΔΔCT method. Mean ± SEM.