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. Author manuscript; available in PMC: 2014 Sep 4.
Published in final edited form as: J Am Chem Soc. 2013 Aug 22;135(35):10.1021/ja407739y. doi: 10.1021/ja407739y

Figure 1.

Figure 1

A. Literature precedent involving the tagging of conventional functional groups.5 B. Identification of a challenge: the tagging of unactivated C–H bonds. C. Designing an azide-containing fluoroalkylsulfinate salt that converts a heteroaromatic C–H bond into a linker for bioconjugation.