Table 2.
Intra-granular components | |||||||
---|---|---|---|---|---|---|---|
Ibuprofen
(%) |
Croscarmellose
(%) |
Polyvinyl pyrrolidone
(%) |
Polyethylene glycol
1000 (%) |
Glucose
(%) |
Sucrose
(%) |
Formulation | Series |
— | — | — | 15.26 | 61.06 | — | F1 | A |
— | — | — | 14.97 | 59.89 | — | F2 | |
— | — | — | 12.72 | 63.60 | — | F3 | |
— | — | — | 10.90 | 65.42 | — | F4 | |
— | — | — | 19.08 | 57.24 | — | F5 | |
— | — | — | 25.44 | 50.88 | — | F6 | |
— | — | — | 15.26 | — | 61.06 | F7 | |
— | — | — | 19.08 | — | 57.24 | F8 | B |
— | — | 15.26 | — | 61.06 | — | F9 | |
— | — | 2.94 | — | 73.38 | — | F10 | |
— | — | 2.80 | — | 70.02 | — | F11 | |
— | — | 2.61 | — | 65.21 | — | F12 | |
— | — | 2.42 | — | 60.40 | — | F13 | |
— | — | 2.42 | — | 60.40 | — | F14 | C |
― | 20.51 | 2.42 | ― | 60.40 | ― | F15 | |
16.67 | 20.51 | 2.42 | ― | 60.40 | ― | F16 | |
16.67 | 24.51 | 2.42 | ― | 56.40 | ― | F17 | |
16.67 | 28.51 | 2.42 | ― | 52.40 | ― | F18 | |
16.67 | 12.255 | 2.42 | ― | 56.40 | ― | F19 | |
12.50 | 18.38 | 1.82 | ― | 42.30 | ― | F17a | D |
12.50 | 18.38 | 1.82 | ― | 42.30 | ― | F17b | |
16.67 | 24.51 | 2.42 | ― | 56.40 | ― | F20 | E |
12.50 | 18.38 | 1.82 | ― | 42.30 | ― | F20a | |
30.77 | 24.51 | 2.42 | ― | 42.30 | ― | F21 | F |
15.385 | 12.255 | 1.21 | ― | 21.15 | ― | F21a | |
73.07 | 24.51 | 2.42 | ― | ― | ― | F22 | |
36.535 | 12.255 | 1.21 | ― | ― | ― | F22a |