Table 1.
Effects of Treatment of Mentha piperita leaves extract on general characteristics of the fructose induced hyperlipidemia and hyperinsulinemia
| Group | Normal | Fructose-fed control |
Fructose-fed treated with extract
(100 mg/Kg) |
Fructose-fed treated with extract
(250 mg/Kg) |
|---|---|---|---|---|
| Characteristic | ||||
| Body weight (g/rat) | 228 ± 9.564 | 334 ± 12.453 | 292 ± 13.483 | 273 ± 8.561** |
| Water intake (mL/rat/day) | 43 ± 7.325 | 46 ± 5.687 | 41 ± 7.230 | 47 ± 4.624 |
| Food intake (g/rat/day) | 15.8 ± 2.781 | 18.7 ± 1.569 | 15.9 ± 1.989 | 16.5 ± 1.349 |
| Serum Glucose (mg/dL) | 75.4 ± 7.620 | 117.3 ± 4.945* | 86.0 ± 5.060* | 76.4 ± 6.514** |
| Serum Insulin (μU/mL) | 17.1 ± 4.385 | 42.5 ± 4.660* | 35.6 ± 6.898 | 31.8 ± 2.358 |
| Serum Cholesterol (mg/dL) | 83.1 ± 7.556 | 135 9.125* | 103.5 ± 11.105 | 94.33 ± 6.647** |
| Serum HDL (mg/dL) | 33.8 ± 2.548 | 14.7 ± 2.088* | 22.6 ± 2.765** | 29.8 ± 1.797** |
| Serum Triglyceride (mg/dL) | 99.1 ± 11.649 | 166.8 ± 8.920* | 99.8 ± 8.495** | 90.8 ± 9.793** |
| SerumVLDL (mg/dL) | 19.8 ± 2.330 | 33.3 ± 1.784* | 19.9 ± 1.699** | 18.1 ± 1.959** |
| Serum LDL (mg/dL) | 42.6 ± 8.710 | 87.4 ± 10.538* | 53.7 ± 11.858** | 40.5 ± 15.157 |
| HDL Ratio | 37.7 ± 3.903 | 12.2 ± 2.504* | 45.1 ± 7.622** | 58.8 ± 3.956** |
| Atherogenic index: | 4.7 ± 0.878 | 11.5 ± 1.112* | 3.4 ± 0.438** | 2.7 ± 0.369** |
n = 6; *: Significantly different from normal control, p < 0.05; **: Significantly different from fructose-fed control, p < 0.05.