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Phase II quantitative anticonvulsant data in mice (IP).
| Compds. | R | ED 50 (mg·Kg -1 ) | TD 50 (mg·Kg -1 ) | PI(TD 50 /ED 50 ) |
|---|---|---|---|---|
| 3f | -C7H15 | 84.9 (74.3-97.0) | 509.2 (476.3-544.4) | 6.0 |
| Valproate | - | 272.0 (247.1-338.8) | 426.1 (369.4-450.3) | 1.6 |
| Carbamazepine | - | 11.8 (8.5-16.4) | 76.1 (55.8-103.7) | 6.4 |
