Table 1.
Superoxide dismutase (SOD), glutathione peroxidase (GPX) and catalase (CAT) activities in erythrocytes of ASE, AAE and SOE treated Alloxan-diabetic rats
| Groups | Dose (mg/Kg bw) | Blood antioxidant enzymes | ||
|---|---|---|---|---|
| SOD (U/g Hb) | GPX (U/g Hb) | CAT (K/g Hb) | ||
| NC | - | 2943 ± 104.4 a | 51.31±4.2a | 1.57 ± 0.6a |
| DC | - | 1945.8 ± 21.6 | 33.11 ± 3.74 | 0.541 ± 0.011 |
| ASE+D | 500 | 3125.4 ± 54.2 a | 42.2 ± 5.21b | 0.882 ± 0.12 c |
| AAE+D | 500 | 3214.3 ± 83.2 a | 47.5 ± 4.2 a | 0.839 ± 0.09 c |
| SOE+D | 250 | 2591 ± 9.13 a | 41.33 ± 2.08 b | 0.598 ± 0.04 e |
| Met+D | 100 | 2118.1 ± 29.7 c | 37.31 ± 5.51 e | 0.551 ± 0.07 e |
NC: normal control, DC: diabetic control, ASE+D: diabetic rats treated with 500 mg kg−1 BW of Allium sativum bulbs methanolic extracts, AAE+D: diabetic rats treated with 500 mg kg−1 BW of Allium ascalonicum bulbs methanolic extracts, SOE+D: diabetic rats treated with 250 mg kg−1 BW of Salvia officinalis leaves methanolic extracts respectively, Met+D: Diabetic rats treated with metformin. Each value is the mean ± SD of ten separate experiments. a p < 0.0001 vs. DC. b p < 0.001 vs. DC. c p < 0.043 vs. DC. e p > 0.156 vs. DC