Table 2.
Important laboratory parameters observed in IV Paracetamol and IV Fentanyl groups on day 0, day 3 and day 6 of the study
|
Lab Test
(scale) |
Drug for Infusion (IV) |
Day 0
(pre-infusion) Mean (SD*) |
Day 3
(3 day after infusion) Mean (SD*) |
Day 6
(6 day after infusion) Mean (SD*) |
significance |
|---|---|---|---|---|---|
| AST (mg/dL) |
Paracetamol | 42.9 (32.3) | 42.3 (30.2) | 41.2 (27.5) | NS |
| Fentanyl | 42.0 (41.5) | 41.4 (35.9) | 43.5 (36.8) | ||
| p= value | 0.94 | 0.93 | 0.82 | ||
| ALT (mg/dL) |
Paracetamol | 30.9 (27.7) | 40.2 (29.4) | 41.5 (29.9) | NS |
| Fentanyl | 36.4 (37.9) | 39.7 (38.0) | 41.5 (38.1) | ||
| p = value | 0.60 | 0.96 | 1.00 | ||
| Bilirubin Total (mg/dL) |
Paracetamol | 1.01 (0.89) | 0.87 (0.48) | 0.78 (0.3) | NS |
| Fentanyl | 0.98 (0.78) | 0.87 (0.51) | 0.74 (0.35) | ||
| p= value | 0.91 | 1.00 | 0.70 | ||
| Bilirubin Direct (mg/dL) | Paracetamol | 0.31 (0.27) | 0.35 (0.28) | 0.28 (0.16) | NS |
| Fentanyl | 0.31 (0.28) | 0.35 (0.27) | 0.38 (0.28) | ||
| p= value | 0.70 | 0.96 | 0.20 | ||
| PT (Second) | Paracetamol | 14.0 (1.8) | 14.6 (3.3) | 15.6 (4.3) | NS |
| Fentanyl | 13.4 (1.02) | 13.4 (1.2) | 13.5 (1.04) | ||
| p= value | 0.18 | 0.14 | 0.044 | ||
| PT (Second) | Paracetamol | 36.9 (11.0) | 34.9 (7.9) | 34.7 (6.1) | NS |
| Fentanyl | 34.7 (3.8) | 35.5 (3.8) | 34.5 (4.7) | ||
| p= value | 0.39 | 0.73 | 0.92 | ||
| INR (Number) |
Paracetamol | 1.17 (0.28) | 1.3 (0.45) | 1.2 (0.39) | NS |
| Fentanyl | 1.17 (0.15) | 1.16 (0.15) | 1.15 (0.16) | ||
| p= value | 0.97 | 42.3 (30.2) | 0.14 |