Table 1.
Acute effects of ASE, AAE and SOE on postprandial blood glucose in alloxan-diabetic Wistar rats
| Groups | Dose |
Postprandial blood glucose (mg/dL)
|
|||||
|---|---|---|---|---|---|---|---|
|
(mg kg
−1
BW) | |||||||
| 0 | 1 | 3 | 5 | 8 | 24 | ||
| NC | - | 68.2±2.3b | 71.2±6.4b | 64.8±2.8b | 74.4±3.3b | 75.2±4.5b | 70.34±4.4b |
| DC | - | 314.2±10.3c,d | 318.7±14.4d | 309.34±15.2 | 303.22±8.2 | 312.32±12.3 | 322.21±10.3 |
| ASEa+D | 250 | 309.53±15.7c,d,e | 307.45±11.4d,e | 289.41±9.4a,b,d | 281.62±12.3a,b | 274.82±8.3a,b | 282.65±9.1a,b |
| ASEb+D | 500 | 311.4±12.5c,d,e | 309.61±8.9d,e | 287.34±11.8a,b,d | 259.3±12.6a,b,d | 246.52±9.6a,b | 241.66±9.2a,b |
| AAEa+D | 250 | 308.44±14.4c,d,e | 316.4±13.1d,e | 311.64±8.2e | 285.53±10.3a,b | 287.39±8.51a,b | 283.3±14.2a,b |
| AAEb+D | 500 | 311.24±13.2c,d,e | 304.81±7.1d,e | 291.5±8.9a,b,d | 273.24±11.7a,b | 270.41±10.7a,b | 274.23±7.4a,b,c |
| SOEa+D | 250 | 314.67±11.1c,d,e | 289.6±10a,b | 269.33±9.2a,b,c | 290.33±15.5a | 292.3±9.2a,b | 271±11.5a,b,c |
| SOEb+D | 500 | 320.66±19.5c,d,e | 318.66±14d,e | 298.33±13.5a,d,e | 310.5±9e | 320±15.13e | 324.3±14.2e |
| Ac+D | 20 | 318.2±10.2c,d,e | 265.2±7a,b | 256.2±7.3a,b | 186.2±14.8a,b | 199.4±7a,b | 266.8±7.8a,b |
| Glib+D | 5 | 312.4±14.3c,d,e | 303.11±7.9e | 291.6±12.8a,b | 245.73±9.1a,b | 174.32±9.6a,b | 129.44±8.2a,b |
NC: normal control, DC: diabetic control, ASEa+D and ASEb+D: diabetic rats treated with 250 and 500 mg kg−1 BW of Allium sativum bulbs methanolic extracts respectively, AAEa+D and AAEb+D: diabetic rats treated with 250 and 500 mg kg−1 BW of Allium ascalonicum bulbs methanolic extracts respectively, SOEa+D and SOEb+D: diabetic rats treated with 250 and 500 mg kg−1 BW of Salvia officinalis leaves methanolic extracts respectively, Ac+D: diabetic rats treated with acarbose, Glib+D: diabetic rats treated with glibenclamide. Each value is the mean ± SD. of ten separate experiments. a p < 0.05 vs. Time 0, b p < 0.05 vs. DC, c p > 0.1 vs. Ac+D, d p > 0.1 vs. Glib+D, ep > 0.06 vs. DC