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Effects induction time (cell density at induction time g L-1 DCW) on the rhIFN-γ production (g L-1 rhIFN-γ) (■) and rhIFN-γ productivity (g L-1 h-1 rhIFN-γ) at fed-batch cultures of E.coli BL21 (DE3) (pET3a-ifnγ). The black and dotted lines denote inducer concentrations of 2.25×10-3 and 1.13×10-3 g L-1 g-1 IPTG per DCW, respectively
