Table 2.

Odds ratios^afor PCOS according to body weight class, overall and by race/ethnicity

	Weight Class
	Underweight/Normal	Overweight	Moderately Obese	Extremely Obese	P-trendb	P-interactionc
Diagnosed PCOS-NIH
Overall	1.0 (reference)	3.85 (3.04–4.88)	10.25 (8.16–12.84)	23.10 (18.66–28.61)	<0.001
By Race/Ethnicity						0.133
Non-Hispanic White	1.0 (reference)	4.53 (2.89–7.11)	13.72 (8.86–21.25)	29.62 (19.58–44.81)	<0.001
Black	1.0 (reference)	2.79 (1.23–6.34)	2.98 (1.15–7.73)	10.14 (4.95–20.77)	<0.001
Hispanic White	1.0 (reference)	3.64 (2.56–5.17)	10.55 (7.60–14.65)	20.38 (14.85–27.97)	<0.001
Asian/Pacific Islander	1.0 (reference)	1.32 (0.44–3.95)	7.27 (3.09–17.14)	21.09 (9.66–46.05)	<0.001
Other/Multiple races	1.0 (reference)	2.49 (0.55–11.24)	4.99 (1.10–22.72)	12.03 (3.15–45.87)	<0.001
All PCOS-NIH
Overall	1.0 (reference)	2.95 (2.53–3.44)	6.73 (5.78–7.83)	14.65 (12.73–16.86)	<0.001
By Race/Ethnicity						0.126
Non-Hispanic White	1.0 (reference)	2.87 (2.13–3.87)	6.14 (4.48–8.43)	14.28 (10.73–19.02)	<0.001
Black	1.0 (reference)	3.78 (2.29–6.34)	3.78 (2.09–6.83)	11.77 (7.36–18.82)	<0.001
Hispanic White	1.0 (reference)	2.76 (2.21–3.46)	7.30 (5.91–9.01)	13.76 (11.23–16.87)	<0.001
Asian/Pacific Islander	1.0 (reference)	2.46 (1.33–4.56)	7.69 (4.22–14.01)	17.32 (9.62–31.18)	<0.001
Other/Multiple races	1.0 (reference)	1.16 (0.37–3.62)	4.62 (1.85–11.52)	10.36 (4.52–23.72)	<0.001

^aOdds ratios, 95% confidence intervals, and P-values estimated from multivariate logistic regression models that adjust for age (years), proportion of individuals with an education below high school in the neighborhood, and beneficiary status of Medi-Cal or other state subsidized support programs (yes or no). Overall estimates also adjust for race/ethnicity.

^bP-trend evaluated on categorical weight class variable using likelihood ratio test.

^cP-interaction evaluated using likelihood ratio test for race/ethnicity * weight class interaction term excluding unknown race/ethnicity from data.