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. Author manuscript; available in PMC: 2013 Oct 30.
Published in final edited form as: J Immunol. 2010 Mar 31;184(9):10.4049/jimmunol.0904076. doi: 10.4049/jimmunol.0904076

FIGURE 4.

FIGURE 4

Repertoire ‘holes’ develop during LIP in absence of Tregs. Three different T cell populations were adoptively transferred into individual RAG−/− mice: CD4 T cells (CD8-CD44loCD25-), CD8 T cells (CD4-CD44loCD25-), or bulk T cells (CD44loCD25-). Representative CDR3 length bar graph histograms from for individual Vβ10Jβ TCR segments are shown in this figure. Panels A and B represent different experiments. Histograms from the same individual animal are shown per experiment and the specific experimental condition.