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. 2013 Nov;132(5):e1384–e1394. doi: 10.1542/peds.2013-0755

TABLE 3.

Overview of Participants in the CARRA Registry (February 2013)

Number of Participants % Current or Previous Exposure to Biologicsa % Current or Previous Exposure to DMARDS or Immune Suppressive Medicationsb
Total number enrolled 8211 34.5 75.9
Specific diagnosesc
 JIA 5823 42.9 72.3
 SLE 834 11.5 95.1
 Mixed connective tissue disease 141 23.4 92.9
 Juvenile dermatomyositis 552 11.2 94.4
 Vasculitis 170 27.1 82.4
 Systemic sclerosis 48 2.1 87.5
 Localized scleroderma 316 2.9 86.7
 Sjogren syndrome 16 18.8 81.3
 Autoinflammatory disease 52 25.0 23.1
 Idiopathic uveitis 70 55.7 82.9
 Sarcoidosis 45 53.3 77.8
 Pain syndromes 144 2.1 5.6

DMARDS, disease-modifying antirheumatic drugs; SLE, systemic lupus erythematosus.

a

Includes abatacept, adalimumab, anakinra, belimumab, canakinumab, certolizumab, etanercept, golimumab, infliximab, rilonacept, rituximab, and tocilizumab. Excludes intravenous immunoglobulin.

b

Includes azathioprine, cyclophosphamide, cyclosporine, hydroxychloroquine, leflunomide, methotrexate, mycophenylate mofetil, sulfasalazine, and tacrolimus. Excludes corticosteroids.

c

Additional diagnoses added as of February 2, 2012 include Sjogren syndrome, autoinflammatory diseases, and idiopathic uveitis.