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Downregulation of AMOG correlates with worse clinical outcome. Kaplan–Meier (KM) analysis comparing overall survival between patients whose GBM had intermediate (black) AMOG expression (from 2-fold upregulated to 6-fold downregulated) and patients whose GBM had downregulated (green) AMOG expression (6-fold or more downregulated) (P < .001). Expression data represent mRNA microarray expression data from TCGA database queried in February 2012.
