Table 1.

AMOG is heterogeneously expressed in gliomas

	AMOG Positivity
Tumor grade	+	++	+++
Grade II	4	2	2
Grade III	3	3	3
Grade IV	35	16	8

Immunohistochemical evaluation of AMOG expression in different grades of gliomas (astrocytomas) in tissue arrays containing 59 GBM, 9 grade III anaplastic astrocytomas, and 8 grade II astrocytomas. The normal human brain cortex was used as a positive control, and the white matter was used as a negative control. AMOG positivity is defined by categorizing the percentage of tumor cells that stain positive for AMOG into 3 categories: + for 0%–25%, ++ for 26%–75%, and +++ for 76%–100%. The numbers of samples corresponding to 1 of the 3 categories of staining are recorded in this table for each grade of glioma.