Table 1. Baseline clinical characteristics of CRISPS-1 (1995-6) cohort subjects with and without incident cancers.
Incident cancer | No cancer | p-value | |
---|---|---|---|
N | 205 | 2688 | -- |
Sex (% Male) | 120 (58.5%) | 1290 (48.0%) | 0.004 |
Age (years) | 56±11.6 | 45±12.5 | <0.001 |
Ever smoker (%) | 73 (35.6%) | 667 (24.9%) | 0.001 |
Alcohol drinker (%) | 73 (35.6%) | 994 (37.1%) | 0.678 |
Body Mass Index (kg/m2) | 24.9±3.96 | 24.1±3.57 | 0.002 |
Obesity (%) | 45 (22.1%) | 432 (16.1%) | 0.015 |
Waist Circumference (cm) | <0.001b | ||
Male | 86.6±10.2 | 82.7±9.45 | |
Female | 78.6±9.08 | 75.0±9.35 | |
Central obesity (%) | 75 (36.6%) | 658 (24.5%) | <0.001 |
Hypertension (%) | 74 (36.1%) | 449 (16.7%) | <0.001 |
Diabetes (%) | 36 (18.1%) | 241 (9.4%) | <0.001 |
HOMA-IRa,c | 1.21 (0.79-2.11) | 1.11 (0.72-1.79) | 0.119 |
Fasting insulin (mIU/L) | 5.10 (3.30-7.80) | 4.90 (3.20-7.40) | 0.683 |
Dyslipidemia (%) | 151 (73.7%) | 1707 (63.6%) | 0.004 |
Data are expressed as mean±SD unless stated otherwise; a log-transformed before analysis; b sex-adjusted p-value; c excluded 164 subjects with missing data; obesity was defined as BMI ≥27.5kg/m2; central obesity was defined as WC>90 cm for men,>80cm for women; ever smoker was defined as current or former smoker; alcohol drinker was defined as self-reported regular consumption of alcohol.