Table 1. Datasets used for training and testing CanDrA.
Datasets | Cancer Type | #Drivers | #Passengers | Used for |
GBM.Ex | GBM | 1529 (COSMIC) | 1259 (COSMIC) | Training |
GBM.S1 | GBM | 67 (TCGA+COSMIC) | 95 (TCGA) | Test |
GBM.S2 | GBM | 67 (TCGA+COSMIC) | 490 (CCLE) | Test |
OVC.Ex | OVC | 1768 (COSMIC) | 8075 (COSMIC) | Training |
OVC.S1 | OVC | 61 (TCGA+COSMIC) | 246 (TCGA) | Test |
OVC.S2 | OVC | 61 (TCGA+COSMIC) | 462 (CCLE) | Test |
Listed are the numbers of driver and passenger mutations for glioblastoma multiforme (GBM) and ovarian carcinoma (OVC) curated from the Catalogue of Somatic Mutations in Cancer (COSMIC), The Cancer Genome Atlas (TCGA), and the Cancer Cell Line Encyclopedia (CCLE).