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. 2013 Apr 10;14(6):527–536. doi: 10.4161/cbt.24348

Table 2. Number of surviving animals following treatment with BocNHO and CBI-indole2.

Day BocNHO CBI-indole2 Vehicle
0
9
9
10
11
8
7
10
20
7
0
10
32 7 0 9

Following treatment of lung-tumor-burdened mice with BocNHO or CBI-indole2, increased survival was observed in the 60 µg/kg BocNHO and vehicle treatment groups compared with 60 µg/kg CBI-indole2, suggesting reduced toxicity of the BocNHO prodrug (Fig. 6A).