Table II.

Univariate and multivariate analyses of survival and clinical and laboratory variables.

Variables	Univariate analysis P-value	Multivariate analysis P-value
Age (<60 vs. ≥60 years)	0.009	0.023
Gender (female vs. male)	0.415	0.690
Histology (NSCLC vs. SCLC)	0.446	0.104
Stage of disease (non-metastatic vs. metastatic)	0.109	0.053
LDH (<450 vs. ≥450 IU/l)	0.001	0.263
Hemoglobin (<12 vs. ≥12 g/dl)	0.412	0.158
Leucocyte (<11,000 vs. ≥11,000/mm3)	0.829	0.023
Platelet (<350,000 vs. ≥350,000/mm3)	0.763	0.105
Sedimentation (<40 vs. ≥40 mm/h)	0.524	0.116
Response to chemotherapy (yes vs. no)	<0.001	0.004

Significant P-values (<0.05) are highlighted in bold. NSCLC, non-small-cell lung cancer; SCLC, small-cell lung cancer; LDH, lactate dehydrogenase.