Table 6. Single-marker analysis of GWAS Alzheimer’s disease susceptibility SNPs in independent data.
Chr | SNP | Position | Gene | Minor | Major | p-value | Odds Ratio |
1 | rs3818361 | 207784968 | CR1 | A | G | 4.28×10−4 | 1.07 |
2 | rs744373 | 127894615 | BIN1 | G | A | 9.63×10−1 | 1.00 |
6 | rs9349407 | 47453378 | CD2AP | C | G | 6.80×10−2 | 1.15 |
7 | rs11767557 | 143109139 | EPHA1 | C | T | 7.73×10−2 | 0.89 |
8 | rs11136000 | 27464519 | CLU | T | C | 8.63×10−2 | 0.88 |
11 | rs610932 | 59939307 | MS4A | T | G | 7.97×10−1 | 0.98 |
11 | rs3851179 | 85868640 | PICALM | T | C | 3.85×10−2 | 0.86 |
19 | rs3764650 | 1046520 | ABCA7 | G | T | 3.81×10−1 | 1.11 |
19 | rs429358 | 45411941 | APOE | C | T | 1.57×10−48 | 3.58 |
19 | rs3865444 | 51727962 | CD33 | A | C | 5.22×10−1 | 1.05 |