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. 2013 Oct 30;8(10):e78411. doi: 10.1371/journal.pone.0078411

Table 3. Correlation of treatment options with tumour control and overall survival.

Total Tumour control at 4–7months Survival (No./%)
Therapy combinations No./% No Lesion Residual Alive Dead
1. EBRT alone 78(37.3) 65 (40.1) 13 (27.7) 49 (62.8) 29 (37.2)
1+ External boost 47(22.5) 28 (17.3) 19 (40.4) 24 (51.0) 23 (49.0)
1+ Brachy 18(8.6) 15 (9.3) 3 (6.4) 14 (77.8) 4 (22.2)
1+ chemo 52(24.9) 41(28.3) 11 (23.4) 45 (86.5) 7 (13.5)
1+ brachy + chemo 14(6.7) 13 (8.0) 1 (2.1) 13 (92.8) 1 (7.1)
Total/ p-value 209(100) p<0.014 p<0.001

Most patients received only the initial EBRT (37.8%), while 24.9% and 8.6% got additional chemotherapy and brachytherapy respectively. Only 6.7% of patients received combined treatment of EBRT, brachytherapy and chemotherapy. The kind of treatment options the patient received seemed to significantly affect tumour response and overall patient survival as shown here. On adjusting for age and HIV status through multivariate cox proportional hazards regression analysis and multinomial logistic regression, this statistical significance was maintained.