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. 2013 Oct 30;8(10):e78411. doi: 10.1371/journal.pone.0078411

Table 5. Correlation of FIGO staging and histological diagnosis with survival.

Alive n/% Dead n/% P-value
Staging
1A (2) 1 (50.0) 1 (50.0)
1B (13) 10 (76.9) 3 (23.1)
IIA (19) 16 (84.2) 3 (15.8)
IIB (69) 59 (85.5) 10 (14.5) 0.001
IIIA (35) 21(60.0) 14 (40.0)
IIIB (50) 33 (66.0) 17 (34.0)
IV A (13) 4 (30.8) 9 (69.2)
IV B (8) 1 (12.5) 7 (87.5)
Total. 145 (69.4) 64 (30.6)
HPE (SCC) results
Well Differentiated 37 (27.6) 7 (12.3)
 Moderately 56 (41.8) 30 (52.6)
 Poorly 36 (26.9) 19 (33.3) 0.046
 Keratinizing 2 (1.5) 1 (1.8)
Large non-Keratinizing 3 (2.2) 0 (0.0)
 Total. 134 (70.2) 57 (29.8)

Patients with poorly differentiated SCC were more than 2.5 times likely to die as compared to those with well differentiated SCC, while those with more advanced disease staging had as expected, higher death rates (p<0.46, and 0.001 respectively). Even after adjusting for age and HIV status using multivariate cox proportional hazards regression analysis and multinomial logistic regression, the disease stage was significantly associated with overall survival.