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. 2013 Oct 30;8(10):e78344. doi: 10.1371/journal.pone.0078344

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© 2013 Shi et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

(A) Elisa assay was used to detect VEGF secretion changes after transfection of miR-200c mimics into A549 cells. Bevacizumab (B) and su1498 (C) were applied to block VEGF-VEGFR2 pathway. Then clonogenic assays were carried out to examine the radiosensitization effect of miR-200c after VEGF-VEGFR2 blockage. Each experiment was repeated three times. Standard errors of the mean are shown by error bars.