Figure 4. Monocytic populations in B6.WT and B6.CCR7^-/- mice at day 28 after infection with L. major.

(A) Flow cytometry was used to determine monocytic populations in the footpad, lymph node and spleen according to their CD11b and Ly6C expression. (B) The percentage of the total cell number recovered from each tissue is shown for B6.WT (closed circles) and B6.CCR7^-/- (open circles) mice for each monocytic population. The percentage of cells in each population expressing CCR2 (C), iNOS (D) and Ly6G (E) was determined. One representative analysis of three experiments; Experimental group size: n=5 mice/genotype; *p<0.05; **p<0.01.