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. 2013 Oct 30;8(10):e79014. doi: 10.1371/journal.pone.0079014

Figure 1. Examples of representative scatter plot patterns of multiplex ligation-dependent probe amplification (MLPA) analysis for the EGFR gene.

Figure 1

Gain or loss (peak ratio cut off, <0.8 or >1.2) of exons in EGFR gene were represented by red squares. Green square indicated within neutral peak ratio of EGFR gene. Three white squares indicate specific probe for Y chromosome (105 bps), the L858R (281 bps) and the T790M mutations (246 bps). Blue squares represent control probes. ‘HETD’, hemizygous deletion; ‘GAIN’, copy gain; ‘AMP’, amplifications; ‘HLAMP’, high-copy amplifications.