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. 2013 Oct 30;8(10):e79014. doi: 10.1371/journal.pone.0079014

Table 3. Molecular Characteristics of Triple Negative Breast Cancers (n = 105).

Number of cases (%) EGFR copy number change EGFR mutation KRAS mutation TP53 mutation
61 (58.1%) N
25 (23.8%) N +
2 (1.9%) N + a +
1 (1.0%) N + b
6 (5.7%) I
5 (4.8%) I +
2 (1.9%) I†
2 (1.9%) D
1 (1.0%) D +
105 1 (1.0%) 2 (1.9%) 33 (31.4%)

'−', wild type; '+', mutant type; 'D', decreased copy number (hemizygous deletion); ‘N’, normal copy number; 'I', increased EGFR copy number (single copy gain, amplification and high-copy number amplification); † single exon amplification; a p.Gly12Val and p.Gly12Asp; b Deletion on Exon 19. BRAF gene mutation was not detected in all cases