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. 2013 Oct 30;8(10):e77292. doi: 10.1371/journal.pone.0077292

Table 2. Enriched GO terms in response to TCDD treatment in zebrafish liver (p<0.01).

Category Term Count % P-Value Fold Enrichment
Biological protein folding 19 2.98 1.05E-06 3.94
process cellular macromolecule catabolic process 24 3.77 4.61E-05 2.59
macromolecule catabolic process 26 4.08 5.61E-05 2.44
proteolysis involved in cellular protein catabolic process 22 3.45 7.17E-05 2.65
cellular protein catabolic process 22 3.45 7.17E-05 2.65
modification-dependent protein catabolic process 20 3.14 1.65E-04 2.66
modification-dependent macromolecule catabolic process 20 3.14 1.65E-04 2.66
protein catabolic process 22 3.45 2.53E-04 2.43
cell cycle 19 2.98 4.11E-04 2.56
protein maturation by peptide bond cleavage 4 0.63 8.39E-04 17.76
proteolysis 41 6.44 1.40E-03 1.66
protein transport 26 4.08 1.59E-03 1.96
establishment of protein localization 26 4.08 1.59E-03 1.96
protein localization 27 4.24 1.80E-03 1.91
response to bacterium 8 1.26 2.08E-03 4.33
intracellular transport 19 2.98 2.14E-03 2.22
cellular protein localization 15 2.35 4.82E-03 2.33
cellular macromolecule localization 15 2.35 5.13E-03 2.31
Cellular endoplasmic reticulum 42 6.59 1.19E-13 3.67
component proteasome complex 16 2.51 2.67E-09 6.93
cytosol 21 3.30 6.39E-07 3.65
endoplasmic reticulum part 14 2.20 6.83E-06 4.57
endoplasmic reticulum membrane 11 1.73 1.89E-04 4.25
nuclear envelope-endoplasmic reticulum network 11 1.73 3.44E-04 3.96
proteasome core complex 6 0.94 4.41E-03 5.31
Molecular unfolded protein binding 12 1.88 2.85E-05 4.83
function oligosaccharyl transferase activity 4 0.63 5.94E-04 19.98
acid-amino acid ligase activity 12 1.88 1.74E-03 3.06
threonine-type peptidase activity 6 0.94 2.23E-03 6.24
threonine-type endopeptidase activity 6 0.94 2.23E-03 6.24
dolichyl-diphosphooligosaccharide-protein lycotransferase activity 3 0.47 4.64E-03 24.98
ligase activity, forming carbon-nitrogen bonds 13 2.04 5.65E-03 2.50
translation initiation factor activity 8 1.26 5.92E-03 3.63
heme binding 12 1.88 8.31E-03 2.50
RNA binding 20 3.14 9.61E-03 1.89