Table 3. Significantly regulated pathways in zebrafish after TCDD treatment, by GSEA analysis with cutoff FDR<0.25.

Pathways	NES	NOM p-value	FDR q-value
G1 to S cell cycle reactome	1.94	<0.001	0.024
HSA04110 cell cycle	1.9	<0.001	0.025
Cell cycle KEGG	1.86	0.003	0.031
Proteasome pathway	1.81	0.007	0.053
HSA03050 Proteasome	1.74	0.007	0.115
HSA03010 Ribosome	−2.31	<0.001	<0.001
Ribosomal proteins	−2.21	<0.001	0.001
HSA04020 Calcium signaling pathway	−1.85	0.005	0.126
Prostaglandin synthesis regulation	−1.81	0.005	0.167
ST FAS signaling pathway	−1.81	0.007	0.139
ST T cell signal transduction	−1.79	<0.001	0.135
HSA04650 Natural killer cell mediated cytotoxicity	−1.76	0.007	0.160
HSA04660 T cell receptor signaling pathway	−1.75	0.008	0.152

Note: NES, normalized enrichment scores; NOM p-value, nominal p-value for enrichment; FDR, false discovery rate.