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. 2013 Oct 30;8(10):e76251. doi: 10.1371/journal.pone.0076251

Figure 2. LOH and copy neutral LOH (Uniparental Disomy) events.

Figure 2

A: Segmental UPD events spanning multiple microRNA regions in chromosome 4 in patient 9F. B: LOH event in chromosome 17 of the same sample above. LOH is associated with copy number variations. C: Target Prediction analysis of miRNAs exhibit the probable involvement of known signaling pathways in colorectal cancer. Y-axis represents the numerical score indicative of predictive value. D: TPM3 and MUC1 are affected by UPD events in patient 7F. E: MYC region sustain LOH events and copy gains in patient 10F.