Table II.
MS-HRM assay of peripheral blood and colorectal tissue samples of CRC patients.
| MGMT, n | MLH1, n | |||||
|---|---|---|---|---|---|---|
|
|
|
|||||
| Frequencies of methylation (%) | Leukocytes | Normal tissue | Tumor tissue | Leukocytes | Normal tissue | Tumor tissue |
| 0 | 37 | 35 | 31 | 32 | 30 | 31 |
| 0–1 | 0 | 2 | 1 | 0 | 2 | 2 |
| 1–5 | 5 | 4 | 2 | 7 | 1 | 2 |
| 5–25 | 0 | 3 | 3 | 2 | 9 | 5 |
| 25–50 | 1 | 0 | 0 | 3 | 1 | 2 |
| 50–100 | 1 | 0 | 2 | 0 | 0 | 1 |
| 100 | 0 | 0 | 5 | 0 | 1 | 1 |
MS-HRM, methylation-sensitive high-resolution melting; CRC, colorectal cancer; MGMT, DNA repair gene O6-methylguanine-DNA methyltranserferase; MLH1, DNA mismatch repair gene mutator L homologue 1.