Figure 5.

Overexpression of β-spectrin in the fat body caused fat body atrophy and lethality. Much of the space within a wild-type larva is occupied by lobes of fat tissue (left). Larvae overexpressing β-spectrin (UAS-β-spec⁹⁵) at 25° ultimately die by third instar, at which time the fat body has substantially atrophied, leaving larvae with large empty spaces (*).