Figure 2.

Splenocytes from B6pfp→F1 mice exhibit Fas-dependent antihost CTL activity. Antihost CTL activity from control BDF1 (open circles), B6wt→F1 (closed circles), and B6pfp→F1 (closed triangles) mice is shown for (a) L1210 Fas-positive, (b) P815 Fas-dull, and (c) L1210 Fas-negative targets at four successive E/T ratios. Target expression of murine Fas is shown in d–f. Isotype-matched irrelevant Ig was used for background staining (shaded histograms). Similar results were obtained in an additional independent experiment.