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Kinetics of spontaneous IFN-γ and IL-10 production in control F1 and GVHD mice. Splenocytes were tested for spontaneous in vitro IFN-γ or IL-10 production by acute and pfp GVHD mice at 1 week of disease (upper) and by chronic and pfp GVHD mice at 6 weeks of disease (lower). Values are shown as mean ng/mL ± SE for IFN-γ and mean U/mL ± SE for IL-10 at a supernatant dilution of 1:2 (n = 5 mice per group). AP < 0.05 compared with control F1 mice.
