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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Curr Opin Biotechnol. 2013 Aug 2;24(5):10.1016/j.copbio.2013.07.003. doi: 10.1016/j.copbio.2013.07.003

Figure 1. Mechanotransductive components of embryonic tendon cells.

Figure 1

ETCs may sense and transduce mechanical signals between cells via direct cell-to-cell contacts such as cadherin (purple) and connexin (orange), and from the surrounding ECM via integrins (red and green). Downstream, cytoskeletal components that link to these transmembrane proteins may transduce forces to the nucleus to regulate gene and protein expression.